Big Y

Big Y Chromosome Not Significantly Influences Outcomes of in vitro Fertilization and Embryo Transfer

大Y染色体对体外受精与胚胎移植的影响

Objective: To evaluate the influence of big Y chromosome on the outcomes of in vitro fertilization and embryo transfer.

目的：探讨在体外受精与胚胎移植中大Y染色体对其受精方式及结局的影响。

The relationship between big Y chromosome and infaust pregnancy

大Y染色体与不良妊娠关系的探讨

Conclusion: Big Y chromosome has no significant influence on the development of embryos and the outcome of pregnancy.

结论：大Y染色体对胚胎发育及近期妊娠结局无明显影响。

There were 2 cases of abnormal sex chromosomes, 2 cases of big Y chromosomes and 7 cases of small Y chromosomes in the non obstructive azoospermic patients. No correlation was found between EGF and fructose in the seminal plasma.

非梗阻性无精子症组性染色体异常2例，大Y2例，小Y7例，精浆表皮生长因子、果糖两者间无相关性。

Study on Genetics for Big Y Chromosome

大Y染色体的遗传学探讨

Results: According to the patients ′ cytogenetics examination, it is found there are 11 cases abnormal chromosomal karyotypes, including 6 cases of chromosome translocation, 2 cases of 47, XXY, 3 cases of big Y chromosome.

结果发现异常核型11例，其中染色体易位6例、2例47，XXY、3例大Y染色体。

Results: 550 cases of Y chromosome abnormality were observed in 4,238 patients, accounting for 12.98%, including 497 cases of big Y chromosome abnormality;

结果：共检出Y染色体异常核型550例，占全部被检者12.98%，其中大Y染色体异常497例；

Then were big Y chromosome, four cases, accounting for 7.02% of patients studied and 17.39% of those with ACK: 46, XY/ 47, XXY and 47, XXY, one case for each type.

其次为大Y染色体4例，检出率为7.02%，占异常核型的7.39%。46，XY/47，XXY和47，XYY各1例，检出率为1.75%，占异常核型的4.35%。

While according to previous statistics, the percentage of big Y chromosome in the male patients of reproductive abnormalities is up to 2.18%-21.73%.

据统计，大Y染色体在生殖异常的男性患者中的比例达2.18%-21.73%。